Dr. Simphiwe Mandlesilo
Specialist Neurologist
MB ChB (UCT) - University of Cape Town
FC Neurol (SA) - Fellow of the College of Neurologists of South Africa
MMed (Wits) - Masters in Medicine, University of the Witwatersrand
HPCSA Reg: MPO721638 | Practice No: 1075187
Reg No: 2023/508839/21
Bringing world-class neurological expertise to the West Rand community with compassion, clarity, and evidence-based care.
"Diagnosis without clarity isn't care"
This philosophy guides every consultation. Dr. Mandlesilo believes that patients deserve not just a diagnosis, but a clear understanding of their condition, realistic treatment expectations, and a management plan they can actively participate in.
Professional Background
Training, experience, and commitment to excellence
Education & Training
- • MB ChB - University of Cape Town
- • FC Neurol (SA) - Fellow of the College of Neurologists of South Africa
- • MMed - Masters in Medicine, University of the Witwatersrand
- • Advanced training in clinical neurology
- • Evidence-based practice expertise
Hospital Affiliations
- • Life Flora Hospital, Roodepoort
- • Netcare Pinehaven Hospital Krugersdorp
- • Mayo Clinic Consulting Rooms
- • Full inpatient care privileges
Areas of Expertise
- • Memory disorders & dementia
- • Epilepsy & seizure management
- • Headache & migraine care
- • Movement & balance disorders
Community Engagement
- • Serving the West Rand community
- • Medical education contributions
- • Media health awareness efforts
- • Patient advocacy focus
Media & Recognition
Dr. Mandlesilo has been featured in local and national media
Roodepoort Record
Local healthcare profile
News24
National health features
DRUM Magazine
Healthcare professional spotlight
Clinical Approach
Dr. Mandlesilo's practice is built on three core principles: evidence-based decision-making, clear communication, and coordinated care.
Every patient receives a thorough neurological assessment, followed by a detailed discussion of findings and treatment options. Diagnostic uncertainty is acknowledged openly, and management plans are adjusted based on response and patient preference.
For patients requiring hospital admission, Dr. Mandlesilo provides direct continuity of care at both Life Flora Hospital and Netcare Pinehaven Hospital Krugersdorp, ensuring seamless transitions between outpatient and inpatient settings.